Published January 2001 | Version v1
Journal article Metadata-only

Oligomeric proteins: modulation of UV-sensitivity and regularities of photochemical transformations

Creators

  • 1. Voronezhskij Gosudarstvennyj Univ., Voronezh (Russian Federation)

Description

Results of research devoted to the study of photophysical and photochemical transformations of some compound proteins of oxidative, antioxidant, transport and immune systems of body under conditions of different microenvironment (presence of chemical modificators, the change of pH, temperature, doses and spectral composition of ultraviolet irradiation) have been analysed. Methods and the degree of modulation of UV-sensitivity of proteins of the mentioned systems have been discussed. Conditions, on which the used chemical agents show photoprotective and photosensitizing effect on protein molecules, have been found

Abstract (Russian)

Проанализированы результаты исследований по изучению фотофизических и фотохимических превращений некоторых сложных белков окислительной, антиоксидантной, транспортной и иммунной систем организма в условиях различного микроокружения (присутствие химических модификаторов, варьирование величин рН, температуры, доз и спектрального состава УФ-излучения). Обсуждаются способы и степень модуляции УФ-чувствительности белков названных систем: выявлены условия, при которых используемые химические агенты оказывают по отношению к белковым макромолекулам фотопротекторный и фотосенсибилизирующий эффекты

Additional details

Additional titles

Original title (Russian)

Олигомерные белки: модуляция UV-чувствительности и закономерности фотохимических превращений

Publishing Information

Journal Title
Radiatsionnaya Biologiya, Radioehkologiya
Journal Volume
41
Journal Issue
1
Journal Page Range
p. 78-103
ISSN
0869-8031
CODEN
RBIREJ

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
33019927
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BLOOD SERUM; COMPLEMENT; HEMOGLOBIN; LACTATE DEHYDROGENASE; MAN; MODULATION; PEROXIDASES; PHOTOCHEMICAL REACTIONS; PHOTOSENSITIVITY; PROTEIN STRUCTURE; SUPEROXIDE DISMUTASE; SWINE; ULTRAVIOLET RADIATION
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY FLUIDS; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; DOMESTIC ANIMALS; ELECTROMAGNETIC RADIATION; ENZYMES; GLOBINS; HEMIACETAL DEHYDROGENASES; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; MAMMALS; MATERIALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; OXIDOREDUCTASES; PIGMENTS; PORPHYRINS; PRIMATES; PROTEINS; RADIATION EFFECTS; RADIATIONS; SENSITIVITY; VERTEBRATES

Optional Information

Notes
75 refs.; 3 tabs.; 20 figs.