Published 1990
| Version v1
Report
Fluorine-18 fluoroalkyl derivatives of carazalol: Potential ligands for the in vivo studies of the β-adrenergic receptor
Description
Carazalol is an antagonist for the beta-adrenergic receptor and has one of the highest association constants known for the receptor. Fluorine-18 labelled carazalol would be useful in PET studies, so the authors have synthesized a series of alkyl carazalol derivatives which the authors have subsequently radiofluorinated. In vitro and in vivo studies of these derivatives are underway
Additional details
Publishing Information
- Imprint Title
- Eighth international symposium on radiopharmaceutical chemistry. Abstracts: Final report
- Imprint Pagination
- 458 p.
- Journal Page Range
- p. 381.
- Report number
- DOE/ER/60968--1
Conference
- Title
- 8. international symposium on radiopharmaceutical chemistry.
- Dates
- 24-29 Jun 1990.
- Place
- Princeton, NJ (United States).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 23029824
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference, Non-conventional Literature
- Descriptors DEI
- CHEMICAL PREPARATION; EVALUATION; FLUORINE 18; HYDROLYSIS; IN VITRO; LABELLING; LIGANDS; MOLECULAR STRUCTURE; RADIOPHARMACEUTICALS; RECEPTORS; SYMPATHOMIMETICS
- Descriptors DEC
- AUTONOMIC NERVOUS SYSTEM AGENT; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CHEMICAL REACTIONS; DECOMPOSITION; DRUGS; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; NANOSEC LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; SOLVOLYSIS; SYNTHESIS
Optional Information
- Secondary number(s)
- CONF-9006363--Absts.