Published August 1997
| Version v1
Journal article
Regioselective hydrogen isotope exchange reaction in benzoic acid and its alkali metal salts
- 1. Chiba Univ. (Japan). Faculty of Pharmaceutical Sciences
Description
The hydrogen isotope exchange reaction of benzoic and acid its alkali metal salts with deuterium oxide was studied in the presence of RhCl3·3H2O. The products were analyzed by 1H- and 13C-NMR spectroscopies. High regioselectivity of the exchange at the ortho positions was established, and the extent of deuterium labeling and the distribution of d0, d1, and d2 were determined. The reaction mechanism was briefly discussed. (author)
Additional details
Publishing Information
- Journal Title
- Radioisotopes (Tokyo)
- Journal Volume
- 46
- Journal Issue
- 8
- Journal Page Range
- p. 513-519.
- ISSN
- 0033-8303
- CODEN
- RAISAB
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 28071118
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Descriptors DEI
- BENZOIC ACID; HEAVY WATER; HYDROGEN TRANSFER; ISOTOPIC EXCHANGE; NMR SPECTRA; RHODIUM CHLORIDES
- Descriptors DEC
- CARBOXYLIC ACIDS; CHLORIDES; CHLORINE COMPOUNDS; DEUTERIUM COMPOUNDS; HALIDES; HALOGEN COMPOUNDS; HYDROGEN COMPOUNDS; MONOCARBOXYLIC ACIDS; ORGANIC ACIDS; ORGANIC COMPOUNDS; OXYGEN COMPOUNDS; RHODIUM COMPOUNDS; SPECTRA; TRANSITION ELEMENT COMPOUNDS; WATER