Published 1989 | Version v1
Book

Peptide labelling with sulphur-35

  • 1. Sherbrooke University (Canada). Faculty of Medicine, Department of Pharmacology

Description

Examples are presented which show the radioactive labelling of peptides with (35S)Met. This aminoacid is incorporated into the peptide sequence either as a N-protected active ester on the N-terminus of an appropriately protected peptide or introduced C-terminally by using an activated, protected peptide and free (35S)Met. As peptide protecting groups is proposed the reduction sensitive but HF-stable NO2Z groups. As examples are presented the preparations of (35S)Met-enkephalin and of AC(35S)Met-ANF. (author). 8 refs.; 4 figs

Part of:
Synthesis and applications of isotopically labelled compounds 1988

Additional details

Publishing Information

Publisher
Elsevier.
Imprint Place
Amsterdam (Netherlands)
ISBN
0-444-87368-6
Imprint Title
Synthesis and applications of isotopically labelled compounds 1988
Imprint Pagination
860 p.
Journal Page Range
p. 299-304.

Conference

Title
International symposium on the synthesis and applications of isotopically labelled compounds.
Dates
17-21 Jul 1988.
Place
Innsbruck (Austria).

INIS

Country of Publication
Netherlands
Country of Input or Organization
Netherlands
INIS RN
22049771
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
LABELLING; PEPTIDES; SULFUR 35
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; EVEN-ODD NUCLEI; ISOTOPES; LIGHT NUCLEI; NUCLEI; ORGANIC COMPOUNDS; PROTEINS; RADIOISOTOPES; SULFUR ISOTOPES

Optional Information

Notes
Imprint:Includes author index and subject index.