Published January 2019
| Version v1
Journal article
The Prognostic Significance of p16 Status in Patients With Vulvar Cancer Treated With Vulvectomy and Adjuvant Radiation
Creators
- 1. University Pittsburgh School of Medicine, Pittsburgh, Pennslyvania (United States)
- 2. Department of Radiation Oncology, University of Pittsburgh Hillman Cancer Center, Pittsburgh (United States)
- 3. Department of Pathology, University of Pittsburgh Magee Women's Hospital, Pittsburgh (United States)
- 4. Department of Gynecologic Oncology, University of Pittsburgh Hillman Cancer Center, Pittsburgh (United States)
Description
Vulvar squamous cell carcinoma (VSCC) is a relatively rare malignancy. Human papillomavirus has been implicated as a causative factor for a subset of these patients. The purpose of this study was to evaluate whether p16-positivity (a human papillomavirus surrogate) predicts for better response rates in women who undergo surgery followed by adjuvant radiation therapy (RT).
Additional details
Identifiers
- DOI
- 10.1016/j.ijrobp.2018.08.014;
- PII
- S0360301618335442;
Publishing Information
- Journal Title
- International Journal of Radiation Oncology, Biology and Physics
- Journal Volume
- 103
- Journal Issue
- 1
- Journal Page Range
- p. 152-160
- ISSN
- 0360-3016
- CODEN
- IOBPD3
INIS
- Country of Publication
- United States
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 55057303
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CARCINOMAS; PATIENTS; RADIOTHERAPY; SURGERY; WOMEN
- Descriptors DEC
- ANIMALS; DISEASES; FEMALES; HUMANS; MAMMALS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; PRIMATES; RADIOLOGY; THERAPY; VERTEBRATES
Optional Information
- Copyright
- Copyright (c) 2018 Elsevier Inc. All rights reserved.