Published 1986
| Version v1
Journal article
Autoradiographic localization of opioid receptor types in the rat small intestine
Creators
- 1. Royal Free Hospital School of Medicine, London (England)
Description
The selective mu and delta ligands [3H]DAGO and [3H]DPDPE have been used to investigate the distribution of specific opioid subtypes in the rat small intestine by in vitro autoradiography. There was a greater density of [3H]DPDPE binding at regions of the villi and crypts than [3H]DAGO binding. These results suggest that the opioid receptors located in these regions are predominantly of the delta subtype
Additional details
Publishing Information
- Journal Title
- NIDA Res. Monogr.
- Journal Volume
- 75
- Series
- NIDA Res. Monogr.
- Journal Page Range
- 315-318
- CODEN
- MIDAD
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 19063059
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- AUTORADIOGRAPHY; BIOCHEMICAL REACTION KINETICS; BIOLOGICAL LOCALIZATION; ENDORPHINS; IN VITRO; LIGANDS; RATS; RECEPTORS; SMALL INTESTINE; TRITIUM COMPOUNDS
- Descriptors DEC
- ANIMALS; AUTONOMIC NERVOUS SYSTEM AGENT; BODY; DIGESTIVE SYSTEM; DRUGS; GASTROINTESTINAL TRACT; HYDROGEN COMPOUNDS; INTESTINES; KINETICS; MAMMALS; NEUROREGULATORS; ORGANIC COMPOUNDS; ORGANS; PEPTIDES; POLYPEPTIDES; PROTEINS; REACTION KINETICS; RODENTS; VERTEBRATES