Published January 1976 | Version v1
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Influence of age and physicochemical form on the effects of 239Pu on the skeleton of the rat

Creators

Description

Studies were made of the skeletal distribution and effects of monomeric and polymeric 239Pu injected intravenously in adult, weanling, and newborn rats. Autoradiographs suggested that periosteal deposition of activity was greater in the weanlings than in adults and newborns. Abnormal healing of pathologic fractures was observed only in rats exposed as weanlings. Other histologic changes of bone, including exostosis, necrosis, and epiphyseal abnormalities, were most marked in the weanlings injected with monomer and least evident in the newborns

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Additional details

Publishing Information

Imprint Title
Pacific Northwest Laboratory annual report for 1975 to the ERDA Division of Biomedical and Environmental Research. Part 1. Biomedical Sciences
Imprint Pagination
p. 77-80.
Report number
BNWL--2000(Pt.1)

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
7268520
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Progress Report
Descriptors DEI
AGE DEPENDENCE; AUTORADIOGRAPHY; BONE FRACTURES; DISTRIBUTION; HEALING; HISTOLOGY; INTRAVENOUS INJECTION; PLUTONIUM 239; POLYMERS; RADIONUCLIDE KINETICS; RATS; SKELETON; TISSUES
Descriptors DEC
ACTINIDE NUCLEI; ALPHA DECAY RADIOISOTOPES; ANIMALS; BIOLOGICAL RECOVERY; BODY; DISEASES; EVEN-ODD NUCLEI; HEAVY NUCLEI; INJECTION; INJURIES; INTAKE; ISOTOPES; KINETICS; MAMMALS; NUCLEI; ORGANS; PLUTONIUM ISOTOPES; RADIOISOTOPES; RODENTS; SKELETAL DISEASES; VERTEBRATES; YEARS LIVING RADIOISOTOPES