Published January 1993 | Version v1
Report Open

Molecular genetic study of head and neck cancer

  • 1. Korea Cancer Center Hospital, Seoul (Korea, Republic of)

Description

We analyzed 15 cases of head and neck cancer (13 out of 15 were squqmous cell cancer.) by Southern blotting to identify the possible tumor suppressor gene. Firstly we searched the chromosome 17p with pYNZ22, pMCT35.1 and p144D6. 5 out of 7 informative cases showed loss of heterozygosity implying the loss of tumor suppressor gene near those loci. Afterwards analysis of these 5 cases is needed to identify the presence of tumor suppressor genes and the oncogenetic mechanism. (Author)

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MF available from INIS under the Report Number.

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Additional details

Publishing Information

Imprint Pagination
13 p.
Report number
KAERI/RR--1153/92

INIS

Country of Publication
Korea, Republic of
Country of Input or Organization
Korea, Republic of
INIS RN
24057023
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
CHROMOSOMES; DNA; GENES; GENETICS; MOLECULAR BIOLOGY; NECK; NEOPLASMS
Descriptors DEC
BIOLOGY; BODY; BODY AREAS; DISEASES; NUCLEIC ACIDS; ORGANIC COMPOUNDS