Published December 2018
| Version v1
Journal article
Reception of Sex Steroid Hormones in Thyroid Papillary Cancer Tissue and Relationship with Expression and Content of Transcription Factors Brn-3α and TRIM16
- 1. Russian Academy of Sciences (Russian Federation)
Description
We studied reception of sex steroid hormones in the tissues of thyroid papillary cancer and benign tumor. Enhanced expression of AR and ERβ mRNA reflected malignant tumor growth. Nuclear factors Brn-3α and TRIM16 modulating expression of steroid hormones play an important role in the development of thyroid tumors. It was found that the level of TRIM16 mRNA is associated with the expression of ERβ, which seems to be mediated by its antiestrogen effect.
Additional details
Identifiers
Publishing Information
- Journal Title
- Bulletin of Experimental Biology and Medicine
- Journal Volume
- 166
- Journal Issue
- 2
- Journal Page Range
- p. 237-240
- ISSN
- 0007-4888
- CODEN
- BEXBAN
INIS
- Country of Publication
- United States
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 51091923
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- MESSENGER-RNA; NEOPLASMS; STEROID HORMONES; THYROID; TRANSCRIPTION FACTORS
- Descriptors DEC
- BODY; DISEASES; ENDOCRINE GLANDS; GLANDS; HORMONES; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RNA
Optional Information
- Copyright
- Copyright (c) 2018 Springer Science+Business Media, LLC, part of Springer Nature
- Notes
- http://www.springer-ny.com