Published November 1983
| Version v1
Journal article
Lack of rise in serum prolactin following yttrium-90 interstitial irradiation for acromegaly
- 1. Royal Postgraduate Medical School, London (UK)
Description
The authors have investigated the possibility that the increase in serum PRL levels observed in patients with acromegaly treated with external irradiation could be due to damage to the hypothalamus or portal vessels, by comparing the effects of yttrium-90 interstitial irradiation, which is highly localised and does not normally extend to the hypothalamus, in a similar series of patients. These results are consistent with the hypothesis; a less likely explanation is that an overgrowth of radio-resistant PRL-secreting tumour cells is occurring after external irradiation, but not after yttrium-90 implantation. (author)
Additional details
Publishing Information
- Journal Title
- Clin. Endocrinol.
- Journal Volume
- 19
- Journal Issue
- 5
- Series
- Clin. Endocrinol.
- Journal Page Range
- 557-563
- ISSN
- 0300-0664
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 15030838
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ACROMEGALY; BETA PARTICLES; BIOLOGICAL RADIATION EFFECTS; HYPOTHALAMUS; LTH; PITUITARY GLAND; TUMOR CELLS; YTTRIUM 90
- Descriptors DEC
- ANIMAL CELLS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; BRAIN; CENTRAL NERVOUS SYSTEM; CHARGED PARTICLES; DAYS LIVING RADIOISOTOPES; DISEASES; ENDOCRINE DISEASES; ENDOCRINE GLANDS; GLANDS; GONADOTROPINS; HORMONES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NERVOUS SYSTEM; NUCLEI; ODD-ODD NUCLEI; ORGANS; PEPTIDE HORMONES; PITUITARY HORMONES; RADIATION EFFECTS; RADIOISOTOPES; YTTRIUM ISOTOPES