Synthesis of labeled compounds
Creators
Description
Intermediate compounds labeled with 13C included methane, sodium cyanide, methanol, ethanol, and acetonitrile. A new method for synthesizing 15N-labeled 4-ethylsulfonyl-1-naphthalene-sulfonamide was developed. Studies were conducted on pathways to oleic-1-13C acid and a second pathway investigated was based on carbonation of 8-heptadecynylmagnesium bromide with CO2 to prepare sterolic acid. Biosynthetic preparations included glucose-13C from starch isolated from tobacco leaves following photosynthetic incubation with 13CO2 and galactose-13C from galactosylglycerol-13C from kelp. Research on growth of organisms emphasized photosynthetic growth of algae in which all cellular carbon is labeled. Preliminary experiments were performed to optimize the growth of Escherichia coli on sodium acetate-13C
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Additional details
Additional titles
- Augmented title (English)
- "1"3C, "1"5N
Publishing Information
- Imprint Title
- Biomedical and Environmental Research program of the LASL Health Division. Progress report, January--December 1976
- Journal Page Range
- p. 144-146.
- Report number
- LA--6898-PR
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 9378440
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Resource subtype / Literary indicator
- Progress Report
- Descriptors DEI
- ALGAE; BIOSYNTHESIS; CARBON DIOXIDE; CARBON 13; ESCHERICHIA COLI; ETHANOL; GLUCOSE; ISOTOPIC EXCHANGE; LABELLED COMPOUNDS; LABELLING; METHANE; METHANOL; NITRILES; NITROGEN 15; OLEIC ACID; PHOTOSYNTHESIS; STEROLS; SULFONAMIDES; TOBACCO
- Descriptors DEC
- ALCOHOLS; ALDEHYDES; ALKANES; AMIDES; BACTERIA; CARBOHYDRATES; CARBON COMPOUNDS; CARBON ISOTOPES; CARBON OXIDES; CARBOXYLIC ACIDS; CHALCOGENIDES; CHEMICAL REACTIONS; EVEN-ODD NUCLEI; HEXOSES; HYDROCARBONS; HYDROXY COMPOUNDS; ISOTOPES; LIGHT NUCLEI; MICROORGANISMS; MONOCARBOXYLIC ACIDS; MONOSACCHARIDES; NITROGEN ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC SULFUR COMPOUNDS; OXIDES; OXYGEN COMPOUNDS; PLANTS; SACCHARIDES; STABLE ISOTOPES; STEROIDS; SYNTHESIS