Published 1981 | Version v1
Journal article Metadata-only

Myocardial distribution of I131-labeled hexadecenoic acid in relation to the dog local coronary flow

Creators

  • 1. Centre Hospitalier Regional, 38 - Grenoble (France)
  • 2. Grenoble-1 Univ., 38 (France). Inst. des Sciences Nucleaires

Description

20 anesthetized and thoracotomized dogs are studied. The local myocardial blood flow is measured with sup(99m)Tc human albumin microspheres. The intramyocardial distribution of the 16-I(131)-9-hexadecenoic acid in relation to local blood flow is studied in basal conditions (7 dogs), after experimental infarction (6 dogs) and postischemic reactive hyperhemia (7 dogs). We conclude that during basal condition, after infarction but not during reactive hyperhemia, the distribution of the labeled fatty acid reflect the local variations of blood flow

Abstract (French)

20 chiens anesthesies et thoracotomises sont etudies. Le debit sanguin myocardique local est mesure avec des microspheres d'albumine humaine marquees au sup(99m)Tc. La repartition intramyocardique de l'acide 16-I(131)-hexadecene-9-oique en fonction du debit sanguin local est etudiee dans les conditions basales (7 chiens), apres creation d'un infarctus (6 chiens) et au cours de l'hyperhemie reactionnelle post-ischemique (7 chiens). On conclut que dans les conditions basales et apres infarctus la fixation de l'acide gras marque suit les variations du debit. Par contre, au cours de l'hyperhemie reactionnelle post-ischemique il n'y a pas d'augmentation significative de la fixation de l'acide gras marque

Additional details

Additional titles

Original title (French)
Etude de la fixation myocardique de l'acide 16-I(131) hexadecene-9-oique en fonction du debit sanguin local chez le chien

Publishing Information

Journal Title
J. Fr. Biophys. Med. Nucl.
Journal Volume
5
Journal Issue
3
Series
J. Fr. Biophys. Med. Nucl.
Journal Page Range
153-158

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
13671888
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BLOOD FLOW; CARBOXYLIC ACIDS; DOGS; IODINE 131; LABELLED COMPOUNDS; METABOLISM; MYOCARDIAL INFARCTION; MYOCARDIUM; UPTAKE
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; DAYS LIVING RADIOISOTOPES; DISEASES; HEART; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; MAMMALS; MUSCLES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPES; VERTEBRATES