Effects of low-dose ionizing radiation on tumor-bearing mice and on radiotherapy

We studied the effects of low-dose radiation on tumor-bearing mice and on radiotherapy from hormesis induced by low-dose radiation. The results show that D1 can reduce the tumor rate in mice implanted with tumor cells (P<0.05), and inhibit the tumor growth speed (P<0.05); the effects of radiotherapy on tumor-bearing mice can be enhanced by low-dose radiation. It is further demonstrated that these results are concerned with enhancement of lymphocyte spontaneous proliferation, activity of anti-oxidase, ability of DNA to restore and reduce free radical injury. The above results provide an experimental basis for increasing the efficacy of clinical tumor therapy and alleviating side-effects of radiotherapy