Local intra-arterial thrombolysis in acute ischemic stroke of the anterior circulation
- 1. Shanghai Second Military Medical Univ., Shanghai (China). Changhai Hospital, Dept. of Neurology and Neurosurgery
Description
Objective: To evaluate the safety and efficacy of local intra-arterial thrombolysis (LIT) using urokinase in patients with acute ischemic stroke of the anterior circulation. Methods: Fifty-four patients were treated with LIT using urokinase. The locations of occlusion included 3 of internal carotid artery (ICA), 46 of middle cerebral artery (MCA) and 5 of anterior cerebral artery. Results: Outcome was good in 41 patients (75.9%). Recanalization >50% was obtained in 72.2% of patients and <50% recanalization in 27.8% of patients. Cerebral hemorrhage occurred in 11 patients (20.4%). Four patients died (7.4%). Conclusion: LIT using urokinase can improve the recanalization rate and achieve better functional recovery in patients of acute ischemic stroke
Additional details
Publishing Information
- Journal Title
- Journal of Interventional Radiology
- Journal Volume
- 12
- Journal Issue
- 4
- Journal Page Range
- p. 246-249
- ISSN
- 1008-794X
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 35044712
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BIOMEDICAL RADIOGRAPHY; BLOOD CIRCULATION; CEREBRAL ARTERIES; HEMOLYSIS; IMAGES; IMPLANTS; INJECTION; NECK; RISK ASSESSMENT; SIDE EFFECTS; SYMPTOMS; THERAPY; THROMBOSIS; UROKINASE
- Descriptors DEC
- ARTERIES; BLOOD COAGULATION FACTORS; BLOOD VESSELS; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; CHEMICAL REACTIONS; DECOMPOSITION; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; ENZYMES; FIBRINOLYTIC AGENTS; HEMATOLOGIC AGENTS; HYDROLASES; INTAKE; LYSIS; MEDICINE; NONSPECIFIC PEPTIDASES; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; PEPTIDE HYDROLASES; PROTEINS; RADIOLOGY; VASCULAR DISEASES