Published 2023 | Version v1
Journal article Metadata-only

Fluorine-18 or Gallium-68: The Perspective of PET Radiochemist

Creators

  • 1. Institut mozga cheloveka im. N.P. Behterevoj RAN, Saint-Petersburg (Russian Federation)

Description

Two radionuclides, 18F (T1/2 110 min) and 68Ga (T1/2 68 min), currently play the leading role in the development of positron emission tomography (PET). This review compares the nuclear-physical properties of fluorine-18 and gallium-68 and methods for their preparation, and also discusses the advantages and drawbacks of two competing radionuclides in clinical PET studies using the example of the most popular radiopharmaceuticals.

Abstract (Russian)

На данном этапе развития позитронно–эмиссионной томографии (ПЭТ) ведущую роль играют два радионуклида - 18F (T1/2 110 мин) и 68Ga (T1/2 68 мин). В представленном обзоре сравниваются ядерно-физические свойства фтора-18 и галлия-68 и методы их получения, а также обсуждаются преимущества и недостатки двух конкурирующих радионуклидов в клинических ПЭТ-исследованиях на примере наиболее популярных радиофармпрепаратов.

Additional details

Additional titles

Original title (Russian)
FTOR-18 ILI GALLIJ-68: MNENIE PEHT RADIOKHIMIKA

Publishing Information

Journal Title
Radiokhimiya
Journal Issue
no.2
Journal Page Range
p. 130-149
ISSN
0033-8311

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
55106099
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
EMISSION COMPUTED TOMOGRAPHY; PEPTIDES; POSITRON COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS
Descriptors DEC
COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; LABELLED COMPOUNDS; MATERIALS; ORGANIC COMPOUNDS; PROTEINS; RADIOACTIVE MATERIALS; TOMOGRAPHY

Optional Information

Notes
141 refs., 2 tabs., 9 figs.