Published January 1998 | Version v1
Report Open

166Ho-chitosan as a radiation synovectomy agent - antigen-induced arthritis in rabbits

Creators

  • 1. Korea Cancer Center Hospital, Seoul (Korea, Republic of)

Description

Radiation synovectomy is a noninvasive therapy that has been investigated as an alternative to surgical synovectomy. It has been successfully employed in the treatment of synovitis in rheumatoid arthritis and other inflammatory arthropathies. In this study, we developed experimental animal model for radiation synovectomy. A model system in which a single injection of ovalbumin into the knee joints of previously sensitized rabbits consistently produced a chronic arthritis which was histologically similiar to human rheumatoid arthritis. (author). 8 refs., 8 figs

Availability note (English)

Available from INIS in electronic form

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Additional details

Publishing Information

Imprint Pagination
28 p.
Report number
KAERI/RR--1778/97

INIS

Country of Publication
Korea, Republic of
Country of Input or Organization
Korea, Republic of
INIS RN
29052743
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ANTIGENS; BONE JOINTS; HOLMIUM 166; HOLMIUM COMPOUNDS; RABBITS; RADIOTHERAPY; RHEUMATIC DISEASES; THERAPEUTIC USES
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; DAYS LIVING RADIOISOTOPES; DISEASES; HOLMIUM ISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPES; MAMMALS; MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; RARE EARTH COMPOUNDS; RARE EARTH NUCLEI; SKELETAL DISEASES; SKELETON; THERAPY; USES; VERTEBRATES; YEARS LIVING RADIOISOTOPES