On the protective action of serotonin according to oxyhaemoglobin at ultraviolet irradiation of the solution mixture

The spectral method has been used to show that serotonin in 5x10-5 M concentration protects the native (20 deg C) oxyhemoglobin (1.48x10-5 M) in the case of ultraviolet irradiation of their mixture at the dose of 12.4x104 erg/cm2. The protective action of serotonin is also found in respect to modified thermal effects (45 deg C) with irradiated hemoproteid solutions: the degree of photooxidation of oxihemoglobin molecules in the presence of radioprotector is less than in its absence. The conclusion is made that the protective action of radioprotector can be defined by the formation of serotonin-oxyhemoglobin complex