Published July 2019
| Version v1
Journal article
Copper-catalyzed 1,1-difunctionalization of terminal alkynes: a three-component reaction for the construction of vinyl sulfones
- 1. Collaborative Innovation Center of Suzhou Nano Science and Technology & School of Chemistry and Materials Science in University of Science and Technology of China, Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry & Center for Excellence in Molecular Synthesis of Chinese Academy of Sciences (China)
Description
A copper-catalyzed 1,1-difunctionalization of terminal alkynes was achieved via a three-component reaction, providing a variety of vinyl sulfones with good yields and excellent chemo- and stereoselectivity. Preliminary mechanistic studies indicated that the reaction probably underwent a Cu-catalyzed formal C–H insertion to produce an allene intermediate, which was then trapped by a sulfonyl anion to give the corresponding product.
Additional details
Identifiers
Publishing Information
- Journal Title
- Science China. Chemistry (Print)
- Journal Volume
- 62
- Journal Issue
- 7
- Journal Page Range
- p. 904-908
- ISSN
- 1674-7291
INIS
- Country of Publication
- China
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 54120083
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Descriptors DEI
- ALKYNES; ALLENE; ANIONS; COPPER; SULFONES
- Descriptors DEC
- CHARGED PARTICLES; DIENES; ELEMENTS; HYDROCARBONS; IONS; METALS; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; POLYENES; TRANSITION ELEMENTS
Optional Information
- Copyright
- Copyright (c) 2019 Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature