Published July 2013
| Version v1
Journal article
Synthesis of Water Soluble Analogs of Arylsulfonylimidazolidinone (JSH-2282)
Creators
- 1. Chungnam National Univ., Daejeon (Korea, Republic of)
Description
To improve the water solubility of arylsulfonylimidazolidinone (JSH-2282), a potent anti-cancer agent, two urea derivatives, sodium S-2-3-4-5-S-2-oxo-4-phenylimidazolidin-1-ylsulfonyl indoline-1-carbonyl-phenyl ureido succinate (2a) and sodium S-2-3-4-5-S-2-oxo-4-phenylimidazolidin-1-ylsulfonyl indoline-1-carbonyl phenyl ureido pentanedioate (2b), were synthesized and studied for solubility and anti-cancer activity
Additional details
Publishing Information
- Journal Title
- Bulletin of the Korean Chemical Society
- Journal Volume
- 34
- Journal Issue
- 7
- Series
- 14 refs, 3 figs, 1 tab
- Journal Page Range
- p. 2011-2015
- ISSN
- 0253-2964
INIS
- Country of Publication
- Korea, Republic of
- Country of Input or Organization
- Korea, Republic of
- INIS RN
- 45108442
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- 2-3-PENTANEDIONE; AQUEOUS SOLUTIONS; CARBONYLS; NEOPLASMS; SODIUM; SYNTHESIS
- Descriptors DEC
- ALKALI METALS; DISEASES; DISPERSIONS; ELEMENTS; HOMOGENEOUS MIXTURES; KETONES; METALS; MIXTURES; ORGANIC COMPOUNDS; SOLUTIONS