Published April 1986
| Version v1
Journal article
Effect of some polysaccharides in cyclic nucleotide level and phosphodiesterase activity in organs of mice with lewis' lung carcinoma
Description
This paper describes the results of a study of the effect of the bacterial polysaccharide prodigiosan and the yeast cell membrane bipolymer zymosan on the absolute and relative levels of cAMP, cAMP, and cAMP-dependent phosphodiesterase (PDE) in the thymus, spleen, and lungs of healthy mice and of mice with metastasizing Lewis' lung carcinoma. The cyclic nucleotide concentration was determined by radioimmunoassay. Radioactivity of the samples was studied in an SL-30 liquid scintillation counter. PDE activity was determined by paper chromatography using 8-3H-cAMP as the substrate
Additional details
Publishing Information
- Journal Title
- Bull. Exp. Biol. Med. (Engl. Transl.)
- Journal Volume
- 100
- Journal Issue
- 11
- Series
- Bull. Exp. Biol. Med. (Engl. Transl.).
- Journal Page Range
- 1576-1578
- ISSN
- 0007-4888
- CODEN
- BEXBA
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 18035952
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- AMP; BIOLOGICAL EFFECTS; CARCINOMAS; ENZYME ACTIVITY; EXPERIMENTAL NEOPLASMS; IMMUNE REACTIONS; INTRAMUSCULAR INJECTION; LUNGS; MICE; NUCLEOTIDES; PHOSPHODIESTERASES; POLYSACCHARIDES; RADIOIMMUNOASSAY; SPLEEN; THYMUS; TRITIUM COMPOUNDS; TUMOR CELLS; ZYMOSAN
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BODY; CARBOHYDRATES; DISEASES; ENZYMES; ESTERASES; HYDROGEN COMPOUNDS; HYDROLASES; INJECTION; INTAKE; ISOTOPE APPLICATIONS; LYMPHATIC SYSTEM; MAMMALS; NEOPLASMS; ORGANIC COMPOUNDS; ORGANS; RESPIRATORY SYSTEM; RODENTS; SACCHARIDES; TRACER TECHNIQUES; VERTEBRATES
Optional Information
- Notes
- Cover-to-cover translation of Byulleten' Ehksperimental'noj Biologii i Meditsiny (USSR).