Published July 1983 | Version v1
Journal article

Migration of lymphocytes within the internally irradiated body

  • 1. Akademiya Meditsinskikh Nauk SSSR, Obninsk. Nauchno-Issledovatel'skij Inst. Meditsinskoj Radiologii

Description

In experiments on CBA mice it was shown that migration of 51Cr-labeled spleen lymphocytes, injected intravenously, to lymph nodes of intact recipients was suppressed 6-24 months after the administration of a radiopharmaceutic preparation of selenium-75-selenomethionine in a quantity forming the doses of 1 Gy and 1.5 Gy absorbed within the whole body and lymphoid organs, respectively. Migration of labeled lymphocytes to the liver, kidneys and lungs, as well as their retention in the circulating blood, were increased. As the result of the migration disorders the specific affinity of lymphocytes for peripheral lymphoid tissue decreased

Additional details

Additional titles

Subtitle (English)
Effect of internal #gamma#-irradiation on migrating capacity of splenic lymphocytes labelled with "5"1Cr
Original title (Russian)
Миграция лимфоцитов в организме в условиях внутреннего облучения
Original subtitle (Russian)
Vliyanie vnutrennego #gamma#-oblucheniya na migratsionnye svojstva mechennykh "5"1Cr limfotsitov selezenki.

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
23
Journal Issue
4
Series
Radiobiologiya.
Journal Page Range
493-496
ISSN
0033-8192

Optional Information

Notes
For English translation see the journal Radiobiology (Translation) (USA).