Acquisition method study on 99mTc-MIBI myocardial SPECT

Heart phantom and clinical study of 99mTc-MIBI SPECT with 180 degree (LAO to RAO) data acquisition was carried out and compared with the full 360 degree rotation. Data analyses included myocardial volume and area, defect volume and area. In simple heart phantom study, 360 degree acquisition was more approximate to phantom determined true value (P>0.05). However, when a heart phantom was wrapped in a chest phantom, 180 degree data acquisition was more accordant with true value (P>0.05). In 34 cases with coronary heart disease, all of the quantitative parameters mentioned above were very accordant between 360 degree/6 degree and 180 degree/6 degree, 180 degree/6 degree and 180 degree/3 degree. The defect-to normal wall-count ratio (D/N) was lower in the 180 degree scan (0.235 +- 0.043) than in the 360 degree scan (0.249 +- 0.057) (P<0.05), indicating the lesion site can be better detected by the former method. All of the results suggested that for myocardial SPECT the 180 degree acquisition method can save acquisition time and is more practical in the clinical appliance than 360 degree acquisition