Production of the radiopharmaceuticals labelling albumin nano-colloid with 99mTc for scintiscanning studies of the lymphatic system and bone marrow
Description
The objective of the present work was to carried out the production in Guatemala, of a new radiopharmaceutical in the General Direction of Nuclear Energy for the detection of the cancer, as well as its implementation, the quality control by means of the radiochemical purity, the microbiology control and organoleptic quality , to evaluate the biodistribution in rats and to check its stability. The work was carried out formulating the pharmaco albumin Nano-colloid, then it was labelled with 99mTc, the radiochemical purity was evaluated, measuring the disintegrations in minutes of the 99mTc in an scintillation counter type well, being determined the percentage of union from the 99mTc to the nanocolloid, with a purity bigger than 90%
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Additional details
Additional titles
- Original title (Spanish)
- Produccion del radiofarmaco nano-coloide de albumina marcado con
Publishing Information
- Imprint Pagination
- 83 p.
- Report number
- INIS-GT--003
INIS
- Country of Publication
- Guatemala
- Country of Input or Organization
- Guatemala
- INIS RN
- 31008504
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Thesis
- Descriptors DEI
- LABELLING; NUCLEAR MEDICINE; QUALITY CONTROL; RADIOPHARMACEUTICALS; RATS; TECHNETIUM 99
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CONTROL; DRUGS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MATERIALS; MEDICINE; NUCLEI; ODD-EVEN NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; TECHNETIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES