Advances in experimental research on radiation-induced heart injury in animal models

When radiation was used for the treatment of chest malignant tumor, the heart will be irradiated inevitably, which led to radiation-induced heart disease (RIHD). With the improvement of radiotherapy and chemotherapy, the survival time of cancer patients had been extended Therefore, the research on RIHD had been attracted more and more attention. At present, scholars have not formed a unified understanding of this disease and there is no effective method to prevent its occurrence in clinical practice at home and abroad. Animal model research can provide reliable evidence for clinical treatment and prevention of this disease. For this reason, this paper reviews and analyzes the animal model research of radioactive heart injury in recent years, which aiming to provide reference for the development of follow-up experiments and clinical application. (authors)