Published June 1985 | Version v1
Journal article Metadata-only

An evaluation of the clinical usefulness of amifostine (YM-08310), radioprotective agent

Creators

  • 1. Gunma Univ., Maebashi (Japan). School of Medicine

Description

Radioprotective effect of Amifostine (YM-08310) was evaluated in patients with abdominal and pelvic tumor by the double-blind method and the following results were obtained. 1. YM-group showed a tendency of significant superiority over PL-group in the usefulness. 2. No significant difference in the over-all judgement on improvement of the disease in the course of therapy and the incidence of adverse-reactions was observed between YM-group and PL-group. 3. The incidence of diarrhea in YM-group was less than that in PL-group. However, no significant difference was observed. 4. Judging from the results of the effect on tumor size, YM had no radioprotective effect on tumor tissue. (author)

Additional details

Additional titles

Subtitle (English)
A double-blind placebo-controlled study, 2; abdominal and pelvic tumor

Publishing Information

Journal Title
Nippon Gan Chiryo Gakkai-Shi
Journal Volume
20
Journal Issue
5
Series
Nippon Gan Chiryo Gakkai-Shi.
Journal Page Range
994-1001
ISSN
0021-4671
CODEN
NGCJA

INIS

Country of Publication
Japan
Country of Input or Organization
Japan
INIS RN
17031588
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BLADDER; CARCINOMAS; DOSE-RESPONSE RELATIONSHIPS; EFFICIENCY; GAMMA RADIATION; OVARIES; PATIENTS; RADIATION INJURIES; RADIOPROTECTIVE SUBSTANCES; RADIOTHERAPY; TESTES; UTERUS; X RADIATION
Descriptors DEC
BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DISEASES; DRUGS; ELECTROMAGNETIC RADIATION; FEMALE GENITALS; GONADS; INJURIES; IONIZING RADIATIONS; MALE GENITALS; MEDICINE; NEOPLASMS; ORGANS; RADIATION EFFECTS; RADIATIONS; RESPONSE MODIFYING FACTORS; THERAPY; URINARY TRACT