Published August 1992 | Version v1
Journal article Metadata-only

Kinetic study of ligand exchange reaction between 99mTc-GH and ECD

Creators

  • 1. Jiangsu Inst. of Nuclear Medicine, Wuxi (China)

Description

In order to explore this type of 99mTc-GH and H2S2 ligands exchange reaction as a common method for the preparation of 99mTc-N2S2 complexes, detailed kinetic study of ligand exchange reaction between 99mTc-GH and ECD was carried out. Preliminary results from the study at different ligand concentrations and pH values are presented. The ligand exchange reaction is a second order reaction. Its rate constants being pH dependent were determined as: kpH2 = 1.11 x 104 l·mol-1·min-1, kpH5 1.34 x 104 l · mol-1 · min-1, kpH6 = 2.24 x 104 l · mol-1 · min-1

Additional details

Publishing Information

Journal Title
Nuclear Science and Techniques
Journal Volume
3
Journal Issue
3
Journal Page Range
p. 182-185.
ISSN
1001-8042
CODEN
NSETEC

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
24056328
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CARBOHYDRATES; CHELATING AGENTS; CHEMICAL REACTION KINETICS; ESTERS; ION EXCHANGE; LIGANDS; PH VALUE; TECHNETIUM COMPLEXES; TECHNETIUM 99
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; COMPLEXES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KINETICS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; RADIOISOTOPES; REACTION KINETICS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPLEXES; YEARS LIVING RADIOISOTOPES