Published July 1975 | Version v1
Journal article Metadata-only

Determining liver retention of transuranium elements in living beagles

Creators

  • 1. Utah Univ., Salt Lake City (USA). Radiobiology Div.

Description

A method has been developed whereby the liver content of photon-emitting transuranium elements can be determined in living beagles by a combination of total-body and partial-body counting. Calibration of the system was accomplished through the photon counting of intact dogs and also of the parts of the same animals following autopsy. A determination of the calibration factors for 252Cf, 247Cf, 243Cm, 237Pu, and 141Am has been made. The special case of 252Cf was treated in which a significant fraction of the high energy fission gamma-ray spectrum penetrates the Pb shield employed in partial-body counting, and methods were developed which allow for this effect in the calculation of liver content. Some uniformity of response in the system was evident for all of the emitters which were considered. It is proposed that similar techniques could be applied in the determination of selected organ radioactivity in other species including man. (orig.)

Abstract (German)

Es wurde eine Methode entwickelt, mit der der Gehalt an photonenemittierenden transuranischen Elementen in der Leber lebender Beagles durch kombinierte Ganzkoerper- und Teilkoerperzaehlung bestimmt werden kann. Zur Eichung des Systems wurde der Photonengehalt an lebenden Hunden und an Koerperteilen derselben Hunde nach der Autopsie gemessen. Die Eichungsfaktoren wurden fuer 252Cf, 247Cf, 243Cm, 237Pu, und 241Am bestimmt. Der Sonderfall von 252Cf wurde behandelt in dem ein signifikanter Teil des hochenergetischen Spaltungs-γ-Spektrums die bei der Teilkoerperzaehlung verwendete Pb-Abschirmung durchdringt, und es wurden Methoden entwickelt, die diesen Effekt bei der Berechnung der Ueberkonzentration in Betracht ziehen. Es zeigte sich, dass das System auf die untersuchten Elemente fast gleich reagiert. Aehnliche Methoden koennten auch bei der Bestimmung der Radioaktivitaet in bestimmten Organen anderer Spezies einschliesslich des Menschen Anwendung finden. (orig./AK)

Additional details

Identifiers

DOI
10.1007/bf01328975;

Publishing Information

Journal Title
Radiation and Environmental Biophysics
Journal Volume
12
Journal Issue
2
Series
Radiat. Environ. Biophys.
Journal Page Range
139-145
ISSN
0301-634X

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
6213129
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
AMERICIUM 241; BEAGLES; CALIFORNIUM 247; CALIFORNIUM 252; CURIUM 243; LIVER; RADIONUCLIDE KINETICS; RETENTION; TRACER TECHNIQUES; WHOLE-BODY COUNTING
Descriptors DEC
ACTINIDE NUCLEI; ALPHA DECAY RADIOISOTOPES; AMERICIUM ISOTOPES; ANIMALS; BETA DECAY RADIOISOTOPES; BODY; CALIFORNIUM ISOTOPES; COUNTING TECHNIQUES; CURIUM ISOTOPES; DIGESTIVE SYSTEM; DOGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-EVEN NUCLEI; EVEN-ODD NUCLEI; GLANDS; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; KINETICS; MAMMALS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
2 figs.; 2 tabs.; 3 refs.; Updated automatically by Metadata and Full-Text Enrichment Agent