Glutathione Enhancer Protects Some Biochemical and Haematological Parameters from the Effect of Electromagnetic Field
Creators
- 1. Biological Application Dept., Nuclear Research Centre (NRC) Cairo (Egypt)
- 2. Labelled Compounds Dept., Hot Lab Centre (HLC), Egyptian Atomic Energy Authority, Cairo (Egypt)
Description
The Present study was designed to study the effect of exposure to electromagnetic field (EMF), emitted from a cellular tower for mobile phone on some biochemical and haematological parameters in male albino rats and to evaluate of the possible protective role of the antioxidant glutathione enhancer on the studied parameters. Three groups of rats were studied, the control (unexposed), the exposed and the treated exposed groups. Exposed groups were subjected to EMF at frequency of 900 MHz, with a peak power of about 60 W, power density of 0.05 mW/ cm2 at the site of exposure for 24 h/ day for 8 weeks, at the same time treated group was supplied with oral injection of glutathione enhancer three times weekly. At the end of experiment, serum levels of thyroid stimulating hormone (TSH), calcium (Ca), uric acid, malondialdehyde (MDA) beside, the activity of lactate dehydrogenase (LDH) were measured also, some haematological parameters were estimated. Impairment of TSH and serum calcium was expressed by a decrease in serum levels of the exposed group. Meanwhile, serum level of MDA, uric acid and the activity of LDH were increased by exposure. The haematological studies revealed that, exposure to electromagnetic spectrum induced significant reduction in red blood cell counts (RBC's), and haemoglobin concentration (Hb), meanwhile reticulocyte count (Ret) was elevated. The leucocyte counts (WBC's) and platelets count were not affected by exposure. The study demonstrated that glutathione enhancer can attenuate the side effects of exposure to electromagnetic field.
Additional details
Publishing Information
- Journal Title
- Egyptian Journal of Radiation Sciences and Applications (Online)
- Journal Volume
- 29
- Journal Issue
- 1-2
- Journal Page Range
- p. 33-48
- ISSN
- 2314-8527
INIS
- Country of Publication
- Egypt
- Country of Input or Organization
- Egypt
- INIS RN
- 48081290
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ANTIOXIDANTS; BIOCHEMISTRY; BLOOD CELLS; BLOOD SERUM; ELECTROMAGNETIC FIELDS; GLUTATHIONE; HEMOGLOBIN; INJECTION; LACTATE DEHYDROGENASE; LEUKOCYTES; MALES; RATS; URIC ACID
- Descriptors DEC
- ANIMALS; AROMATICS; AZAARENES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BLOOD PLASMA; BODY FLUIDS; CARBOXYLIC ACIDS; CHEMISTRY; DRUGS; ENZYMES; GLOBINS; HEMIACETAL DEHYDROGENASES; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; HYDROCARBONS; INTAKE; MAMMALS; MATERIALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; OXIDOREDUCTASES; PEPTIDES; PIGMENTS; POLYPEPTIDES; PORPHYRINS; PROTEINS; PURINES; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; RODENTS; VERTEBRATES; XANTHINES