Published November 2019 | Version v1
Journal article

Comparison of Outcomes and Toxicity Between Extreme and Moderate Radiation Therapy Hypofractionation in Localized Prostate Cancer: A Propensity Score Analysis

  • 1. Department of Radiation Oncology, European Institute of Oncology, IRCCS, Milan (Italy)
  • 2. Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan (Italy)
  • 3. Department of Oncology and Hematoncology, University of Milan, Milan (Italy)
  • 4. Division of Epidemiology and Biostatistics, IEO, European Institute of Oncology IRCCS, Milan (Italy)

Description

To compare clinical outcomes and toxicities of 2 radiation therapy (RT) schemes for localized prostate cancer (PCa): extreme hypofractionation (EH; fractions of 6.5-7 Gy to a total dose of 32.5-35 Gy) and the moderate hypofractionation (MH; 26 fractions of 2.7 Gy to a total dose of 70.2 Gy). A propensity score method was used to compare the EH-RT and MH-RT groups.

Additional details

Identifiers

DOI
10.1016/j.ijrobp.2019.07.027;
PII
S036030161933531X;

Publishing Information

Journal Title
International Journal of Radiation Oncology, Biology and Physics
Journal Volume
105
Journal Issue
4
Journal Page Range
p. 735-744
ISSN
0360-3016
CODEN
IOBPD3

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
55057310
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
COMPARATIVE EVALUATIONS; FRACTIONATED IRRADIATION; NEOPLASMS; PROSTATE; RADIOTHERAPY; THERAPEUTIC DOSES; TOXICITY
Descriptors DEC
BODY; DISEASES; DOSES; EVALUATION; GLANDS; IRRADIATION; MALE GENITALS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; THERAPY

Optional Information

Copyright
Copyright (c) 2019 Elsevier Inc. All rights reserved.