Quantitative organ-uptake measurement with a gamma camera
Description
A study was carried out to investigate the use of a gamma camera for quantitative measurement of the absolute radioactivity in internal organs. Phantoms simulating different patient conditions were used to derive the attenuation correction factor and the conversion factor which relates a known radioactive dose to organ activity. The delimitation of the source image was established by means of an isocontour of maximum count rate. A mathematical approach was used for achievement of isosensitivity with depth of the organ and for correction for background. The accuracy of the procedure was proven by the recovery over the stomach area of the ingested activity. The method is applied to the quantitative assessment of the splenic red-cell volume. (orig.)
Abstract (German)
Zu dem vorliegenden Beitrag wird ueber den Einsatz einer Gammakamera zur quantitativen Messung der absoluten Radioaktivitaet in inneren Organen berichtet. Zur Bestimmung des Daempfungs-Korrekturfaktors und des Konversionsfaktors, der das Verhaeltnis zwischen bekannter radioaktiver Dosis und Organaktivitaet angibt, wurden Phantome zur Simulierung unterschiedlicher Patienten herangezogen. Die Begrenzung der Bildquelle erfolgte ueber Isocontour mit maximaler Zaehlrate. Die Hintergrundskorrektur und die Isosensitivitaet je nach Tiefe im Organ wurden auf mathematischem Weg bestimmt. Die Genauigkeit der Methode wurde anhand des Abbaus der inkorporierten Aktivitaet im Magenbereich ueberprueft. Angewendet wird die Methode zur quantitativen Bestimmung der roten Zellen in der Milz. (orig.)Additional details
Publishing Information
- Journal Title
- Eur. J. Nucl. Med.
- Journal Volume
- 4
- Journal Issue
- 3
- Series
- Eur. J. Nucl. Med.
- Journal Page Range
- 223-229
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 10487687
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ACCURACY; COLLIMATORS; GAMMA CAMERAS; GEOMETRY; ISOMERIC NUCLEI; MATHEMATICAL MODELS; ORGANS; PHANTOMS; QUANTITY RATIO; RADIOACTIVITY; SCINTISCANNING; SPLEEN; TECHNETIUM 99; UPTAKE
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CAMERAS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATHEMATICS; MEDICINE; MOCKUP; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPE SCANNING; RADIOISOTOPES; STRUCTURAL MODELS; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES