Published 1986 | Version v1
Book Metadata-only

Production and degradation of AMP in cultured rat skeletal and heart muscle: a comparative study

Creators

  • 1. Tel Aviv University School of Medicine, Tel Aviv

Description

The authors clarify the mechanisms operating in the skeletal and heart muscles to produce and degrade AMP. Rat myotube and cardiomyocyte cultures were prepared and purine synthesis was gauged by the rate of C 14-formate incorporation into purines. It is shown that the cell cultures exhibited capacity for de novo purine synthesis, indicated by incorporation of C 14-formate into purines. The rate of C 14-formate into the cardiomyocyte purines was markedly lower than that in the skeletal muscle myotubes

Additional details

Publishing Information

Publisher
Plenum Press.
Imprint Place
New York, NY (USA)
Imprint Title
Purine and pyrimidine metabolism in man V
Journal Page Range
p. 485-491.

Conference

Title
5. international symposium on human purine and pyrimidine metabolism.
Dates
28 Jul - 1 Aug 1985.
Place
San Diego, CA (USA).

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
18051148
Subject category
S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ADENINES; AMP; BIOCHEMISTRY; BIOLOGICAL PATHWAYS; BIOSYNTHESIS; CARBON 14 COMPOUNDS; CELL CULTURES; COMPARATIVE EVALUATIONS; DECOMPOSITION; ENZYME ACTIVITY; FIBROBLASTS; FORMATES; HEART; MUSCLES; NUCLEOTIDASES; PHOSPHOTRANSFERASES; RADIOENZYMATIC ASSAY; RATS; SKELETON
Descriptors DEC
AMINES; ANIMAL CELLS; ANIMALS; ANTIMETABOLITES; BODY; CARBON COMPOUNDS; CARBOXYLIC ACID SALTS; CARDIOVASCULAR SYSTEM; CHEMICAL REACTIONS; CHEMISTRY; CONNECTIVE TISSUE CELLS; DRUGS; ENZYMES; ESTERASES; EVALUATION; HETEROCYCLIC COMPOUNDS; HYDROLASES; MAMMALS; NUCLEOTIDES; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PHOSPHATASES; PHOSPHORUS-GROUP TRANSFERASES; PURINES; RODENTS; SOMATIC CELLS; SYNTHESIS; TRANSFERASES; VERTEBRATES