Published February 1, 1977 | Version v1
Journal article Metadata-only

Assay of human plasma for nortriptyline by radioacetylation and thin-layer chromatography

Creators

  • 1. Warner-Lambert Research Institute, Morris Plains, N.J. (USA). Dept. of Drug Metabolism

Description

A highly specific and sensitive thin-layer chromatographic method for determining nortriptyline levels in plasma is presented. The procedure involves extracting nortriptyline, acetylating it with radioactive acetic anhydride, resolving acetylnortriptyline by thin-layer chromatography, and measuring its radioactivity

Additional details

Identifiers

DOI
10.1016/s0021-9673(00)93769-5;

Publishing Information

Journal Title
Journal of Chromatography A
Journal Volume
132
Journal Issue
1
Series
J. Chromatogr.
Journal Page Range
45-49
ISSN
0021-9673

INIS

Country of Publication
Netherlands
Country of Input or Organization
Netherlands
INIS RN
8303192
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
ACETYLATION; ANIMAL CELLS; CARBON 14; CARBON 14 COMPOUNDS; DRUGS; LABELLING; RADIOASSAY; THIN-LAYER CHROMATOGRAPHY
Descriptors DEC
ACYLATION; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBON COMPOUNDS; CARBON ISOTOPES; CHEMICAL REACTIONS; CHROMATOGRAPHY; EVEN-EVEN NUCLEI; ISOTOPES; LIGHT NUCLEI; NUCLEI; RADIOISOTOPES; SEPARATION PROCESSES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
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