Analysis of prognostic factors in cases with stage I non-small cell lung cancer treated by radiation therapy

Factors influencing local progression-free rate and prognosis in forty-nine patients with stage I non-small cell lung cancer who were treated by radiation therapy from 1968 to 1991 were analysed by univariate and multivariate methods. No significant factor influencing the local progression-free rate was identified by univariate analysis and also by multivariate analysis. Significant association was found between survival rates and serum albumin, serum lactate dehydrogenase (LDH), pulmonary function test and mediastinal irradiation by univariate analysis. In multivariable analysis using Cox's proportional hazard model, serum albumin, serum LDH and age were significant factors for survival. Serum albumin was especially considered to have the strongest correlation with survival. (author)