Published April 1981
| Version v1
Journal article
Synthesis of isotopically labelled salicylates
Description
[13C-carboxyl]Salicylic acid has been prepared by carbonation of 2-benzyloxybromobenzene followed by reductive debenzylation. Deuterium and tritium labelled salicylic acid and 2H2/13C-salicylic acid were prepared by reduction of the 3,5-dibromo derivatives using Raney Ni-Al. Deuterium labelled salicylic acid containing up to four deuterium atoms was prepared by catalytic exchange with Raney Ni-Al in 5% NaOD/D2O. (author)
Additional details
Publishing Information
- Journal Title
- J. Labelled Compd. Radiopharm.
- Journal Volume
- 18
- Journal Issue
- 4
- Series
- J. Labelled Compd. Radiopharm.
- Journal Page Range
- 593-602
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 12615586
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- ACETYLSALICYLIC ACID; CARBON 13; DEUTERIUM COMPOUNDS; LABELLED COMPOUNDS; SALICYLIC ACID; SYNTHESIS; TRITIUM COMPOUNDS
- Descriptors DEC
- ANALGESICS; CARBON ISOTOPES; CARBOXYLIC ACIDS; DRUGS; EVEN-ODD NUCLEI; HYDROGEN COMPOUNDS; HYDROXY ACIDS; ISOTOPES; LIGHT NUCLEI; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; STABLE ISOTOPES