Analytical methods of biokinetics models with a large compartmental neutral systems. Applications of ICRP 66 and 78 models

New computer programs that include symbolic capability, like Mathematics, can be used to solve analytically large compartmental systems. In this paper some techniques are developed in order to make feasible a computer program that gives not only faster and more accurate solutions, but also analytic solutions for this kind of models. the main idea is to make a partition of subsystem and solve them sequentially. The concept of pseudo-trap compartments in a subsystem is crucial at this point. Impulse (acute), constant, and continuous (such as exponential) intakes are considered. This technique has been applied to develop a computer code (Hum orap) in Mathematic a for solving the ICRP 66 and 78 models. (Author) 11 refs