Published 2001 | Version v1
Computer medium Metadata-only

Assessment of evolutive and prognostic indicators applied to accidental overexposure to ionizing radiation

Creators

  • 1. Centro de Proteccion y Higiene de las Radiaciones, La Habana (Cuba)
  • 2. Autoridad Regulatoria Nuclear, Buenos Aires (Argentina). Lab. de Radiopatologia
  • 3. Hospital Clinico Quirurgico Hermanos Ameijeiras, La Habana (Cuba)

Description

The acute radiation syndrome has been characterized in different ways that involve risk for life and health of the people overexposed to ionizing radiations. This work intends to test a therapeutical total body irradiation (TBI) model as conditioning to bone marrow transplantation. With the purpose of evaluating the applicability of several biological indicators in accidental overexposures, a study was carried out in 46 patients undergoing TBI receiving doses between 10 Gy and 12 Gy. The following parameters were assessed: lipo peroxyde plasmatic levels (TBARS) and total plasma antioxidant activity, reticulocyte maturity index (RMI) and charges in lymphocyte subpopulations. These data suggest that TBARS could provide an useful evolutive indicator in accidental overexposed patients and RMI is an early indicator of bone marrow recovery after radioinduced aplasia

Part of:
Proceedings of the 5. Regional congress on radiation protection and safety; 2. Iberian and Latin American Congress on Radiological Protection Societies; Regional IRPA Congress

Additional details

Additional titles

Original title (Spanish)
Evaluacion de indicadores pronosticos y evolutivos aplicables a situaciones accidentales de sobreexposicion a radiaciones ionizantes

Publishing Information

Imprint Title
Proceedings of the 5. Regional congress on radiation protection and safety; 2. Iberian and Latin American Congress on Radiological Protection Societies; Regional IRPA Congress
Imprint Pagination
[1776 p.]
Journal Page Range
[6 p.]

Conference

Title
5. Regional congress on radiation protection and safety; 2. Iberian and Latin American Congress on Radiological Protection Societies; Regional IRPA Congress
Dates
29 Apr - 4 May 2001
Place
Recife, PE (Brazil)

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
33067318
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ACUTE EXPOSURE; BIOLOGICAL INDICATORS; BIOLOGICAL RADIATION EFFECTS; BONE MARROW; DOSE RATES; DOSE-RESPONSE RELATIONSHIPS; PATIENTS; RADIATION ACCIDENTS; TRANSPLANTS; WHOLE-BODY IRRADIATION
Descriptors DEC
ACCIDENTS; ANIMAL TISSUES; BIOLOGICAL EFFECTS; BODY; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; IRRADIATION; ORGANS; RADIATION EFFECTS

Optional Information

Notes
11 refs., 2 graphs Imprint:Published only in CD-ROM. This electronic proceedings requires the Adobe Acrobat Reader 4.05 (included on this CD) and PC (at least 486 CPU) running Windows 95/98NT