A new polymer gel for magnetic resonance imaging (MRI) radiation dosimetry
Creators
- 1. Department of Radiology, Medical School, University of Athens, Areteion Hospital, 76 Vas. Sofias Avenue, 115 28 Athens (Greece)
- 2. Nuclear and Particle Physics Section, Physics Department, University of Athens, Panepistimioupolis, Ilisia, 157 71 Athens (Greece)
- 3. Nuclear and Particle Physics Section, Physics Department, University of Athens, Panepistimioupolis, Ilisia, 157 71 Athens (Greece).
- 4. Chemistry Department, Section 3, University of Athens, Panepistimioupolis, Ilisia, 157 71 Athens (Greece)
- 5. Medical Physics Department, Hygeia Hospital, Kiffisias Avenue, 24 Erythrou Stavrou, Marousi, 151 23 Athens (Greece)
Description
New composition polymer gels, the N-vinylpyrrolidone argon (VIPAR) gels, were developed and investigated as MRI dosimeters. VIPAR gels were irradiated in the dose range of 0-12 Gy by a 6 MV x-ray linear accelerator and MR-scanned in a 1.5 T magnetic resonance imager. A linear relationship was found between absorbed dose and spin-spin relaxation rate R2. The dose sensitivity was found to be ∼0.1s-1Gy-1 for a gel composition of 4% w/w in N-vinylpyrrolidone, 4% w/w in N,N'-methylene-bisacrylamide, 5% w/w in gelatine type A and 87% w/w in water. This dose sensitivity was stable with time and did not deteriorate even when a boost radiation dose of 2.5 Gy was applied 15 days after the first irradiation. Good reproducibility of these results was observed when a new batch of gels was produced and used for corresponding measurements and analysis. (author)
Additional details
Publishing Information
- Journal Title
- Physics in Medicine and Biology (Online)
- Journal Volume
- 44
- Journal Issue
- 10
- Journal Page Range
- p. 2677-2684
- ISSN
- 1361-6560
INIS
- Country of Publication
- International Atomic Energy Agency (IAEA)
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 31025393
- Subject category
- S61: RADIATION PROTECTION AND DOSIMETRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- DOSIMETRY; GELS; NMR IMAGING; POLYMERS; RADIATION DOSES; RADIATION MONITORING; RADIOSENSITIVITY
- Descriptors DEC
- COLLOIDS; DIAGNOSTIC TECHNIQUES; DISPERSIONS; MONITORING
Optional Information
- Notes
- Refs