Published May 1991 | Version v1
Journal article Metadata-only

Effect of head irradiation with 10 Gy x-rays on the proliferative competence of thymocytes and study on its neuroendocrine mechanism in rats

Creators

  • 1. Dept. of Radiation Biology, N. Bethune Univ. of Med. Sciences (China)

Description

Head irradiation with 10 Gy X-rays in rats caused significant depression of spontaneous incorporation of 3H-TdR in thymocytes accompanied with a decrease in thymus weight in 48 hours. bilateral adrenalectomy completely abolished the above-mentioned effect of head irradiation. Reserpine treatment only prevented the decrease in thymus weight but not the depression of spontaneous incorporation of 3H-TdR in the thymocytes. The thymic changes following head irradiation was speculated to be related with shifts in the sympathetic-adrenomedullary as well as the hypothalamic-pituitary-adrenocortical and thyroid system

Additional details

Publishing Information

Journal Title
Journal of Norman Bethune University of Medical Sciences
Journal Volume
17
Journal Issue
3
Journal Page Range
p. 222-224.
ISSN
0253-3707
CODEN
PEIPDB

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
24005871
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CELL PROLIFERATION; HEAD; NERVOUS SYSTEM; RATS; THYMOCYTES; X RADIATION
Descriptors DEC
ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; BODY; BODY AREAS; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; MAMMALS; RADIATION EFFECTS; RADIATIONS; RODENTS; SOMATIC CELLS; VERTEBRATES