Published November 1990 | Version v1
Journal article Metadata-only

The influence of recombinant granulocytic and macrophagic colony-stimulating factor on halmopoiesis recovery and survival rate of irradiated mice

Creators

  • 1. Institut Biofiziki, Moscow (USSR)

Description

A human recombinant granulocytic-and-macrophagic colony-stimulating factor (rGM-CSF) administered repeatedly to irradiated (10 Gy) CBA mice increased CFUs and CFUGM content, the number of bone marrow granulocytes and erythronormoblasts, and spleen and peripharal blood cellularity. The survival rate of exposed (9.7 Gy) mice repeatedly injected with rGM-CSF increased from 25% (control) to 90%

Additional details

Additional titles

Original title (Russian)
Влияние рекомбинантного гранулоцитарно-макрофагального колониестимулирующего фактора на восстановление кроветворения и выживаемост' облученных мышей

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
32
Journal Issue
6
Series
Radiobiologiya.
Journal Page Range
769-773
ISSN
0033-8192
CODEN
RADOA

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
23016815
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL RECOVERY; BLOOD CELLS; BLOOD FORMATION; BONE MARROW CELLS; CELL PROLIFERATION; CFU; COBALT 60; COLONY FORMATION; MICE; RADIATION DOSES; SPLEEN; THYMUS; TIME DEPENDENCE
Descriptors DEC
ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BODY; BODY FLUIDS; COBALT ISOTOPES; CONNECTIVE TISSUE CELLS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LYMPHATIC SYSTEM; MAMMALS; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIATION EFFECTS; RADIOISOTOPES; RODENTS; SOMATIC CELLS; VERTEBRATES; YEARS LIVING RADIOISOTOPES