Clinical and experimental applications of a new mathematical lung model for krypton 81m inhalation. Chapter 8

An expression for the calculation of the regional ventilation per unit volume has been derived based on a one-lung-unit model and a modification of the height-over-area method. The paper discusses its application to 81Krsup(m) inhalation studies of 49 patients and healthy subjects. The fractional exchange of air per second, obtained by previous workers from wash-out studies with 133Xe and height-over-area method was 13% higher than the normal mean value for V/V for both lungs obtained by the authors, who believed that this difference was due to tissue background correction when 133Xe was used, and to different methods of calculation. (author)