Published November 1982 | Version v1
Miscellaneous Metadata-only

Experimental infection with Klebsiella pneumoniae and its gentamicin therapy in guinea pigs 60Co irradiated with 4 Gy

Creators

  • 1. Slovenska Akademia Vied, Bratislava (Czechoslovakia). Ustav Experimentalnej Farmakologie
  • 2. Ustav Klinickej Onkologie, Bratislava (Czechoslovakia)

Description

Sublethal irradiation was used to suppress the immunity response of the organism. Following the development of infection with Klebsiella pneumoniae the therapeutical effect was compared of intramuscular administration and of inhalation of gentamicin. Intramuscular administration was statistically significant for reducing the mortality of infected guinea pigs as against non-treated animals at days 7 to 10 after irradiation. Administration by inhalation had the same effect between days 12 and 25 after irradiation. The weight and blood counts of the animals were observed during the experiment. (M.D.)

Additional details

Additional titles

Original title (Slovak)
Experimentalna infekcia Klebsiellou pneumoniae a jej terapia gentamicinom u morciat oziarenych 4 Gy

Publishing Information

Imprint Title
Radiation biology II
Imprint Pagination
105 p.
Journal Page Range
p. 7-9.
Report number
INIS-mf--8641

Conference

Title
National radiobiological conference.
Dates
21-25 Nov 1982.
Place
Stary Smokovec (Czechoslovakia).

INIS

Country of Publication
Serbia and Montenegro
Country of Input or Organization
Serbia and Montenegro
INIS RN
14792057
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ANTIBIOTICS; CHEMOTHERAPY; GAMMA RADIATION; GUINEA PIGS; IMMUNOSUPPRESSION; INFECTIOUS DISEASES; PNEUMONIA; SUBLETHAL IRRADIATION
Descriptors DEC
ANIMALS; DISEASES; DRUGS; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MEDICINE; ORGANIC COMPOUNDS; RADIATIONS; RESPIRATORY SYSTEM DISEASES; RODENTS; THERAPY; VERTEBRATES

Optional Information

Notes
Imprint:Radiacna biologia II.;Zbornik prac celostatnej radiobiologickej konferencie.