Published 1996 | Version v1
Miscellaneous Metadata-only

Effect of 60 Co gamma radiation on trehalose level of Saccharomyces boulardii cells

Creators

  • 1. Centro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte, MG (Brazil). Nucleo de Radiobiologia
  • 2. Minas Gerais Univ., Belo Horizonte, MG (Brazil). Dept. de Microbiologia

Description

The medicine Floratil used for diarrhea treatment is composed by lyophilized yeast cells of Saccharomyces boulardii. The action mechanism of this product is unknown. The efficacy of S. boulardii depends on its viability. The increase in the trehalose level in S. cerevisiae cells submitted to a previous sub-lethal level heat shock results in resistance to a lethal shock. The aim of this work was to study weather the cell trehalose level is involved also in the resistance of gamma irradiation. It was noted that the yeast cells surviving to gamma irradiation had more trehalose level than control cells. Apparently there is a positive correlation between of trehalose level and gamma irradiation resistance of S.boulardii cells. (author)

Availability note (English)

Available from the library of the Brazilian Nuclear Energy Commission, Rio de Janeiro

Additional details

Additional titles

Original title (Portuguese)
Efeito da radiacao gama

Publishing Information

Imprint Pagination
5 p.

Conference

Title
6. General congress on nuclear energy
Original Conference Title
6. Congresso geral de energia nuclear
Dates
27 Oct - 1 Nov 1996
Place
Rio de Janeiro, RJ (Brazil)

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
31045035
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference, Non-conventional Literature
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CELL CULTURES; COBALT 60; DISACCHARIDES; GAMMA RADIATION; RADIATION DOSES; SACCHAROMYCES; SURVIVAL CURVES; TEMPERATURE DEPENDENCE
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; CARBOHYDRATES; COBALT ISOTOPES; DOSES; ELECTROMAGNETIC RADIATION; EUMYCOTA; FUNGI; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MICROORGANISMS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; OLIGOSACCHARIDES; ORGANIC COMPOUNDS; PLANTS; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; SACCHARIDES; YEARS LIVING RADIOISOTOPES; YEASTS

Optional Information

Notes
10 refs., 2 figs., 1 tab.