Functional MR Imaging: New tool to predict outcome for cervical carcinoma of uterus treated by concomitant radio chemotherapy?

The treatment of advanced cervix is concomitant radio chemotherapy. Local prognosis and global survival depend on tumoral volume, locoregional extension and radio sensitivity of the lesion. This one is function of tumoral hypoxia, tumoral interstitial pressure and existence of an anaemia. Dynamic contract enhanced MRI (D.C.E.-MRI) allows to quantify pilot vascular parameters of the first two factors. Combined analysis: tumoral volume, anaemia and vascular parameters before and in the course of treatment allows a strong correlation with the risk of local recurrence and global survival. (authors)