Radiation protection to irradiated animals by the treatment of estradiol benzoate and Chinese medicine of tonifying vital energy and eliminating the stagment

The hematopoietic aplasia caused by irradiation was involved in injury of parenchyma cell and microenvironment. This paper reports the combined radiation protective effect of estradiol benzoate, which protects hematopoietic cells, and the Chinese medicine of qi jia dan, a kind of tonifying vital energy and eliminating the stagment prescription for improving microcirculation disturbantces. It showed that the survival rate of the estradiol benzoate-protected group, which was given 3 days before radiation increased by 26.7 percent compared with the untreated group. The chinese medicien administrated to the mice within 3 days after the exposure increased the survival rate by 23.4 percent compared with the control group. The survival rate of the group exposed to 7.5 Gy with combined therapy enhanced 33.4 percent more than the untreated (control) group. The result obtained from dogs indicated the effect of combined therapy group was more better than single therapy group for relieving the symptoms and rerising of blood. The paper concluded that the combined therapy from both parenchyma and microenvironment is more helpful to accelerate the recovery of radiation damage