Moessbauer study of AFe₂O₄ (A = Mn, Fe, and Co) nanoparticles for biomedical applications

The crystallographic and magnetic properties of AFe₂O₄ (A = Mn, Fe, and Co) nanoparticles have been studied for biomedical applications. The powders are prepared by the high thermal temperature decomposition method, and the structural and magnetic properties of the samples are investigated by X-ray diffraction, Vibrating sample magnetometry, and Moessbauer spectroscopy. The crystal structure of the AFe₂O₄ was a single-phase cubic spinel (Fd-3 m). LDH assay was performed to investigate the cytotoxicity of synthesized nanoparticles. In addition, it was confirmed that the magnetic properties did not change even though when the biodegradable polymer (poly(L-lactic acid)) was coated on MnFe₂O₄ nanoparticles, which seemed to be most suitable for thermal therapy, for the purpose of improving biocompatibility. (author)