Radiographic investigation for evaluation of efficacy of treatment for bone metastases and myeloma using bisphosphonates

The purpose of the present work was to study the findings of radiographic in investigations of the skeleton for evaluation of the bone involvement in cancer patients during radio and chemotherapy with the use of bisphoshonates. Clinical laboratory and radiographic investigations were carried out in 13 patients. Of them, 8 suffered from breast cancer, 3 lung cancer, 2 myeloma with generalized skeleton involvement. Radiographic investigation included plain x-ray study, bone scan, x-ray CT and MRI which were performed before and after the treatment. Besides, the amount of blood serum calcium during the treatment was studied