Published 1978 | Version v1
Book Metadata-only

What compound should be used for the detection of brain metastases. Comparison of sup(99m)Tc-gluconate with four other technetium-containing compounds (pertechnetate, DTPA, citrate, bleomycine

Creators

  • 1. Centre Medico-Chirurgical Foch, 92 - Suresnes (France)

Description

This comparative study shows that sup(99m)Tc-gluconate and sup(99m)Tc-DTPA give the best results in the diagnosis of brain metastases, on condition that the examinations are not carried out until 4 to 6 hours after injection. They far outclass pertechnetate and appear more efficient than technetium-containing citrate and bleomycine. The only disadvantages of these compounds are their fast elimination by the kidneys, exposing the kidneys and bladder to higher irradiation doses and the length of the examinations which must be performed 3 to 6 hours after injection with relatively low count rates. However these disadvantages are more than offset by the superiority of the data supplied

Abstract (French)

Cette etude comparative montre que le sup(99m)Tc-gluconate et le sup(99m)Tc-DTPA donnent les meilleurs resultats dans le diagnostic des metastases cerebrales, a condition de pratiquer des examens tardifs 4 a 6 heures apres leur injection. Ces composes surclassent nettement le pertechnetate et paraissent plus performants que le citrate et la bleomycine techneties. Les seuls inconvenients de ces composes sont leur elimination renale rapide entrainant une irradiation renale et vesicale plus elevee, ainsi que l'allongement de la duree des examens qui doivent etre faits 3 a 6 heures apres leur injection avec des taux de comptage relativement faibles. Mais ces inconvenients sont largement compenses par la superiorite des informations qu'ils apportent

Additional details

Additional titles

Subtitle (English)
Chapter 1
Original title (French)
Quel compose utiliser pour la detection des metastases cerebrales. Comparaison du sup(99m)Tc-gluconate avec quatre autres composes techneties (pertechnetate, DTPA, citrate et bleomycine)
Original subtitle (French)
Chapitre 1.

Publishing Information

Publisher
Faculte de Medecine.
Imprint Place
Reims, France
Imprint Title
18. French language symposium on nuclear medicine. Reims, 9-12 June 1977
Journal Page Range
p. 13-16.

Conference

Title
18. French language symposium on nuclear medicine.
Dates
9 - 12 Jun 1977.
Place
Reims, France.

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
10484717
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BLEOMYCIN; BRAIN; COMPARATIVE EVALUATIONS; DIAGNOSIS; DTPA; METASTASES; PERTECHNETATES; SCINTISCANNING; TECHNETIUM 99
Descriptors DEC
AMINO ACIDS; ANTIBIOTICS; ANTIMITOTIC DRUGS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CENTRAL NERVOUS SYSTEM; CHELATING AGENTS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DRUGS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; NERVOUS SYSTEM; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; OXYGEN COMPOUNDS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM COMPOUNDS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPOUNDS; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
Imprint:18. Colloque de medecine nucleaire de langue francaise. Reims, 9-12 juin 1977.