Selective therapy of hepatic cancers using microspheres

This chapter suggests that the use of the hepatic-arterial starch microspheres may be an additional method to deliver more drug to tumors within the liver of a patient undergoing radiation therapy. The concurrent hepatic-arterial infection of a suspension of starch microspheres in a drug solution has the potential of temporarily holding the drug solution in the hepatic-arterial capillary bed, thus allowing more time for the higher drug concentration to move into surrounding tissue. Carustine and mitomycin are examined in conjunction with starch microspheres given via the hepatic artery