Published June 2005
| Version v1
Journal article
Characterization of a tungsten/gas multislit collimator for microbeam radiation therapy at the European Synchrotron Radiation Facility
Creators
- Braeuer-Krisch, E.1, 2, 3, 4, 5, 6, 7
- Bravin, A.1, 2, 3, 4, 5, 6, 7
- Zhang, L.1, 2, 3, 4, 5, 6, 7
- Siegbahn, E.1, 2, 3, 4, 5, 6, 7
- Stepanek, J.1, 2, 3, 4, 5, 6, 7
- Blattmann, H.1, 2, 3, 4, 5, 6, 7
- Slatkin, D. N.1, 2, 3, 4, 5, 6, 7
- Gebbers, J.-O.1, 2, 3, 4, 5, 6, 7
- Jasmin, M.1, 2, 3, 4, 5, 6, 7
- Laissue, J. A.1, 2, 3, 4, 5, 6, 7
- 1. Institute of Pathology, University of Bern, Murtenstrasse 31, 3010 Bern (Switzerland)
- 2. Tecomet Subsidiary, Viasys Healthcare Inc., 170 New Boston Street, Woburn, Massachusetts 01801 (United States)
- 3. Institute of Pathology, Kantonsspital Luzern, 6000 Lucerne (Switzerland)
- 4. P.O.B. 334, Essex, Connecticut 06426 (United States)
- 5. Niederwiesstrasse 13 C, CH-5427 Untersiggenthal (Switzerland)
- 6. Unterriedstrasse 33, 5412 Gebenstorf (Switzerland)
- 7. European Synchrotron Radiation Facility, B.P.220, 38043 Grenoble (France)
Description
Clinical microbeam radiation therapy (MRT) will require a multislit collimator with adjustable uniform slit widths to enable reliable Monte Carlo-based treatment planning. Such a collimator has been designed, fabricated of >99% tungsten [W] by Tecomet/Viasys (Woburn, Massachusetts, USA) and installed at the 6 GeV electron-wiggler-generated hard x-ray ID17 beamline of the European Synchrotron Radiation Facility. Its pair of 125 parallel, 8 mm deep, 0.100 mm wide radiolucent slits, 0.400 mm on center, are perfused with nitrogen gas [N2] to dissipate heat during irradiation. Major improvements in uniformity of microbeam widths and good peak/valley dose ratios combined with a very high dose rate in targeted tissues have been achieved
Additional details
Identifiers
- DOI
- 10.1063/1.1915270;
Publishing Information
- Journal Title
- Review of Scientific Instruments
- Journal Volume
- 76
- Journal Issue
- 6
- Journal Page Range
- p. 064303-064303.7
- ISSN
- 0034-6748
- CODEN
- RSINAK
INIS
- Country of Publication
- United States
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 37035415
- Subject category
- S43: PARTICLE ACCELERATORS; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- COLLIMATORS; DESIGN; DOSE RATES; EQUIPMENT; EUROPEAN SYNCHROTRON RADIATION FACILITY; GEV RANGE 01-10; HARD X RADIATION; IRRADIATION; MONTE CARLO METHOD; NITROGEN; RADIOTHERAPY; SYNCHROTRON RADIATION; TUNGSTEN
- Descriptors DEC
- BREMSSTRAHLUNG; CALCULATION METHODS; ELECTROMAGNETIC RADIATION; ELEMENTS; ENERGY RANGE; GEV RANGE; IONIZING RADIATIONS; MEDICINE; METALS; NONMETALS; NUCLEAR MEDICINE; RADIATION SOURCES; RADIATIONS; RADIOLOGY; REFRACTORY METALS; SYNCHROTRON RADIATION SOURCES; THERAPY; TRANSITION ELEMENTS; X RADIATION
Optional Information
- Notes
- (c) 2005 American Institute of Physics