Published September 1985 | Version v1
Journal article Metadata-only

Changes in endonuclease activity with acid and alkaline pH in rat blood serum after whole-body γ-irradiation

Creators

  • 1. Tsentral'nyj Nauchno-Issledovatel'skij Rentgeno-Radiologicheskij Inst., Leningrad (USSR)

Description

Using the method of electrophoresis in agar gel of superhelical plasmid DNA, which served as a substrate for determining endonuclease activity, the authors showed that the same radiation dose influenced in a different way the activity of acid and alkaline DNAases in rat blood serum. At early times (3-6 h) following irradiation, the activity of acid nucleases increaed whereas that of alkaline DNAases decreased

Additional details

Additional titles

Original title (Russian)
Исследование эндонуклеазной активности при кислых и щелочных значениях pH в сыворотке крови крыс при общем γ-облучении

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
25
Journal Issue
5
Series
Radiobiologiya.
Journal Page Range
676-677
ISSN
0033-8192
CODEN
RADOA

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
17058953
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BLOOD SERUM; CATALYSIS; DNA-ASE; DOSE-RESPONSE RELATIONSHIPS; EARLY RADIATION EFFECTS; METABOLISM; PH VALUE; RATS; TIME DEPENDENCE; WHOLE-BODY IRRADIATION
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; BLOOD; BLOOD PLASMA; BODY FLUIDS; ENZYMES; ESTERASES; EXTERNAL IRRADIATION; HYDROLASES; IRRADIATION; MAMMALS; MATERIALS; ORGANIC COMPOUNDS; PHOSPHATASES; PHOSPHOHYDROLASES; RADIATION EFFECTS; RODENTS; VERTEBRATES